Pemberian Antibiotika pada Pasien IDO (Infeksi Daerah Operasi) RSUP Dr Kariadi Semarang
Antibiotic Administration in Patients with SSI (Surgical Site Infection) Retrospective Study of Dr Kariadi Hospital Semarang
DOI:
https://doi.org/10.35473/jgk.v17i2.767Keywords:
Antibiotika, Infeksi Daerah Operasi, RetrospektifAbstract
Antibiotics are a class of antibacterial drugs that are widely used in inpatient care, either alone or in combination, to prevent IDO. In developed countries, antibiotic use is around 13-37%, whereas in developing countries, it is 30-80%. The purpose of the study is to analyze the use of antibiotics in IDO patients. The research method is retrospective, using patient medical records from 2021-2023, with a quantitative approach and a descriptive study design. The analysis was performed using bivariate analysis with Pearson Product Moment Correlation (r) testing. The study sample consisted of 41 patients diagnosed with IDO. The Pearson Product Moment Correlation analysis showed that the Sig. (2-tailed) value was 0.042 < 0.05, indicating a relationship between variable X (antibiotics administered) and variable Y (infection at the surgical site) in patients undergoing surgery. The r coefficient and scatter plot revealed a positive but weak correlation between antibiotic administration and infection at the surgical site, with a value of 0.319.
ABSTRAK
Antibiotika merupakan golongan obat antibakteri yang banyak di gunakan pada pasien rawat inap secara tunggal maupun kombinasi yang dapat mencegah IDO. Buktinya di negara maju penggunakan antibiotika sekitar 13-37% sedangkan di negara berkembang 30-80%. Tujuan penelitian adalah menganalisis pemberian antibiotika pada pasien IDO. Metode penelitian yaitu retrospektif menggunakan rekam medis pasien 2021-2023, dengan pendekatan kuantitatif dengan jenis penelitian deskriptif. Analisis secara bivariat dengan Uji Korelasi Pearson Product Moment (r). Sampel penelitian sebanyak 41 pasien yang terdiagnosis sebagai IDO. Analisis Korelasi Pearson Product Moment menunjukkan bahwa nilai Sig. (2-tailed) sebesar 0,042 < 0,05, terdapat hubungan antar variabel X (pemberian antibiotika) dan variabel Y (infeksi daerah operasi) pada pasien yang menjalani operasi. Pada koefisien (r) dan scatter plot diperoleh nilai sebesar 0,319 yang menunjukan adanya hubungan positif yang lemah antara pemberian antibiotika dan infeksi daerah operasi.
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References
ABDULQADER, H.H. and SAADI, A.T. (2019) ‘THE DISTRIBUTION OF PATHOGENS, RISK FACTORS AND THEIR ANTIMICROBIAL SUSCEPTIBILITY PATTERNS AMONG POST-SURGICAL SITE INFECTION IN RIZGARI TEACHING HOSPITAL IN ERBIL/KURDISTAN REGION/IRAQ’, Journal of University of Duhok, 22(1), pp. 1–10.
Ahmed, N.J. et al. (2022) ‘Meta-Analysis of Clinical Trials Comparing Cefazolin to Cefuroxime, Ceftriaxone, and Cefamandole for Surgical Site Infection Prevention’, Antibiotics, 11(11). Available at: https://doi.org/10.3390/antibiotics11111543.
Allegranzi B, Bischoff P, de Jonge S, Kubilay NZ, Zayed B, Gomes SM, Abbas M, Atema JJ, Gans S, van Rijen M, Boermeester MA, Egger M, Kluytmans J, Pittet D, S.J. (2016) ‘WHO Guidelines Development Group. New WHO recommendations on preoperative measures for surgical site infection prevention: an evidence-based global perspective’, 2, pp. 276–287. Available at: https://doi.org/10.1016/S1473-3099(16)30398-X.
Alverdy, J.C., Hyman, N. and Gilbert, J. (2020) ‘Elective Surgery in the Era of Asepsis’, Lancet Infectious Diseases, 20(3). Available at: https://doi.org/10.1016/S1473-3099(19)30756-X.Re-examining.
Asia Pacific Society of Infection Control Apsic (2018) ‘Pedoman APSIC Untuk Pencegahan Infeksi Daerah Operasi’, kma - Klinik Management aktuell, 23(S 04), pp. 3–3.
CDC (2022) ‘Surgical Site Infection Event (SSI) Introduction’, National Healthcare Safety Network, (January), pp. 1–39. Available at: https://www.cdc.gov/nhsn/pdfs/ps-analysis-resources/ImportingProcedureData.pdf.
Deka, S. et al. (2020) ‘High Prevalence of Antibiotic-Resistant Gram-Negative Bacteria Causing Surgical Site Infection in a Tertiary Care Hospital of Northeast India’, Cureus, 12(12), pp. 1–10. Available at: https://doi.org/10.7759/cureus.12208.
Dr.K.M. Agus Riyanto, SKM., M.K. (2022) Aplikasi Metodologi Penelitian Kesehatan. Pertama. Yogyakarta: Nuha Medika Yogyakarta.
Hendrawan, A. (2020) Metodologi Penelitian (Teori dan Praktik). Kerawang Barat: CV Saba Jaya.
Kementrian Kesehatan (2017) PMK No 27 Tahun 2017. Available at: https://doi.org/10.1017/CBO9781107415324.004.
Kesehatan, K. (2015) ‘PROGRAM PENGENDALIAN RESISTENSI ANTIMIKROBA DI RUMAH SAKIT’, p. 6.
Lakoh, S. et al. (2022) ‘Incidence and risk factors of surgical site infections and related antibiotic resistance in Freetown, Sierra Leone: a prospective cohort study’, Antimicrobial Resistance and Infection Control, 11(1), pp. 1–12. Available at: https://doi.org/10.1186/s13756-022-01078-y.
Oktaviana Zunnita, Ros Sumarny, J.K. (2022) ‘PENGARUH ANTIBIOTIKA PROFILAKSIS TERHADAP KEJADIAN INFEKSI LUKA OPERASI’, Fitofarmaka Jurnal Ilmiah Farmasi, 16(1), pp. 1–23. Available at: https://doi.org/10.33751/jf.v8i1.1170.
Peraturan BPOM RI No 4 (2018) ‘Rencana Aksi Nasional Pengendalian Resistensi Antimikroba Tahun 2020 - 2024’, Peraturan Menteri Kesehatan Republik Indonesia Nomor 4 Tahun 2018, 151(2), pp. 10–17.
Sartelli, M. et al. (2020) ‘Antibiotic use in low and middle-income countries and the challenges of antimicrobial resistance in surgery’, Antibiotics, 9(8), pp. 1–12. Available at: https://doi.org/10.3390/antibiotics9080497.
Shabrina, A., Lubis, P. and Wintoko, R. (2024) ‘Helmi Ismunandar, Indri Windarti | Infeksi Daerah Operasi Medula | Volume 14| Nomor 2 | Februari’, 14(Cdc), p. 213.
